This Article Full Text (OnlineFirst PDF) All Versions of this Article: 1531003508324614v1 20/3/299    most recent Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Ricotta, J. J. Articles by Malgor, R. D. Search for Related Content PubMed PubMed Citation Articles by Ricotta, J. J. Articles by Malgor, R. D. Pubmed/NCBI databases Medline Plus Health Information Angioplasty Social Bookmarking                         What's this?

A Review of the Trials Comparing Carotid Endarterectomy and Carotid Angioplasty and Stenting

^* To whom correspondence should be addressed. E-mail: Ricotta.Joseph{at}mayo.edu.

	Abstract

In the last decade, carotid artery angioplasty and stenting (CAS) has gained popularity as an alternative to carotid endarterectomy (CEA) for the treatment of carotid stenosis, particularly in patients who are at high operative risk. CAS offers the advantage of being a less invasive procedure, potentially minimizing the risks of wound complications and cranial nerve injury, which may translate into shorter length of hospitalization and less resource utilization. Since the advent of CAS, several randomized controlled trials and carotid stent registry trials have been conducted comparing the outcomes of CEA with those of CAS for the treatment of carotid stenosis in both symptomatic and asymptomatic patients. This review will summarize the results of randomized controlled trials (CAVATAS, WALLSTENT, SAPPHIRE, EVA-3S, SPACE, and CaRESS) as well as pivotal carotid registry studies (ARCHeR, BEACH, CAPTURE, CASES-PMS, CREATE, and CABernET) intended to evaluate the safety and efficacy of CEA and CAS in treatment of carotid stenosis. In addition, it will provide a preview of the current ongoing and future trials examining the safety, applicability, and indications of CAS and CEA (CREST, CAVATAS-2, ACT 1, and TACIT).

First published on September 25, 2008, doi:10.1177/1531003508324614

Perspectives in Vascular Surgery and Endovascular Therapy 2008;20:299.

A more recent version of this article appeared on September 1, 2008


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?