Perspectives in Vascular Surgery and Endovascular Therapy

 

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Perspectives in Vascular Surgery and Endovascular Therapy, Vol. 18, No. 4, 295-298 (2006)
DOI: 10.1177/1531003506297195

Bioabsorbable Stenting for Peripheral Arterial Occlusive Disease

Patrick J. Geraghty, MD

Department of Surgery, Washington University Medical School, St. Louis, Missouri, geraghtyp{at}wustl.edu

Bioabsorbable stents offer an unproven but theoretically appealing means to address the deficiencies of current stent designs. Ideally, these stents would provide early postprocedural scaffolding support yet undergo a predictable process of reabsorption, thus removing the persistent stimulus for neointimal hyperplasia. Prototypes include polymeric formulations and magnesium-based absorbable metal stents. Current and future human trials will ascertain if bioabsorbable stents truly deliver a physiologic advantage in the treatment of peripheral occlusive disease.

Key Words: stent • absorbable implant • lactic acid • magnesium • hyperplasia


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