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Cognitive Impairment and Decline Are Associated With Carotid Artery Disease in Patients Without Clinically Evident Cerebrovascular Disease

Mairnonides Medical Center, 4802 10th Avenue, Admin Bldg, Brooklyn, NY 11219

The authors conducted a study to determine if left carotid artery disease compared with right carotid artery disease is associated With cognitive impairment as determined on the Mlodi aied Miini-Mlental State Examination. Duplex ultrasonography wsJas used to assess internal carotid artery stenosis and intinamedia thickness of the com mon carotid artery in 4.006 rioht-handedr men and women without a history of stroke, transiert ischernic attack, or carotid endarterectomy. Stenosis f 503tor greater of the left internal carotid was associated with cognitive impairment in 32 patients. After statistical evaluat on, the authors concluded that high-grade stenosis of the left internal carotid artery is associated w th cogn tive impairment ano decline but the persistence of the associaton. after ad ustment for right-sided stenosis, is not due to vascular risk factors or atherosc erosis.

Key Words: left carotid aartery disease • cogritive impairment • cerebrovascular disease

Perspectives in Vascular Surgery and Endovascular Therapy, Vol. 17, No. 2, 174-1-175 (2005)
DOI: 10.1177/153100350501700224


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