Perspectives in Vascular Surgery and Endovascular Therapy

 

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Perspectives in Vascular Surgery and Endovascular Therapy, Vol. 17, No. 1, 62-1-63 (2005)
DOI: 10.1177/153100350501700112

Prevention of Disabling and Fatal Strokes by Successful Carotid Endarterectomy in Patients Without Recent Neurologic Symptoms: Randomized Controlled Trial

Wesley S. Moore, MD

UCLA, Division of Vascular Surgery, 10833 Le Conte Avenue, #72-156 CHS, Los Angeles, CA 90095

The hazards and medium-term benefits of carotid endarterectomy were studied in patients with substantial carotid artery narrowing but no neurologic symptoms to determine the balance of surgical risks and long-term benefits. Asymptomatic patients were randomized between immediate CEA and indefinite deferral and were followed for 5 years. The number of deaths among those allocated to immediate CEA was non-significantly greater than among those allocated to deferral. Among patients up to 75 years of age, CEA approximately halved the net 5-year risk of stroke, from about 12% to 6%.

Key Words: carotid endarterectomy • stroke rate • neurologic symptoms


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