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Perspectives in Vascular Surgery and Endovascular Therapy
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Novel Uses of Fibrin Glue in Vascular Surgery

Susanne A. Mikucki, M.D. PH.D.

Howard P. Greisler, M.D.

Cell Biology, Neurobiology and Anatomy, Loyola University Stritch School of Medicine, Maywood, IL

The field of tissue adhesives has recently developed a number of novel clinical applications especially relevant to the surgical specialties. Fibrin glue has been commonly used as a hemostatic agent. In this article, we discuss the most common use of fibrin glue as an adjunct to control hemorrhage, as well as its use as a means to deliver biologic substances to a target. We then will describe some novel applications of fibrin glue in various specialties. Future applications of biologic tissue adhesives will depend on our ability to develop a product that will provide all the benefits discussed without incurring the potential risk of viral transmission.

Key Words: Fibrin glue • tissue adhesives • fibroblast growth factor

Perspectives in Vascular Surgery and Endovascular Therapy, Vol. 11, No. 2, 41-57 (1999)
DOI: 10.1177/153100359901100207
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